New hope for recurrent uterine cancer? drug combo enters early testing
NCT ID NCT06795009
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 30 times
Summary
This early-phase study tests a new drug called zanzalintinib combined with standard chemotherapy (paclitaxel) in people with recurrent high-grade uterine or endometrial cancer. The main goal is to find the safest and most effective dose of the combination. About 36 participants will be enrolled, and researchers will also monitor side effects and how well the tumors respond to treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of California, San Francisco
NOT_YET_RECRUITINGSan Francisco, California, 94143, United States
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University of New Mexico
NOT_YET_RECRUITINGAlbuquerque, New Mexico, 87106, United States
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University of Oklahoma
NOT_YET_RECRUITINGOklahoma City, Oklahoma, 73104, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.