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New drug trial targets rare nasal cancer

NCT ID NCT07527169

First seen Apr 15, 2026 · Last updated Jun 23, 2026 · Updated 13 times

Summary

This phase 2 study tests the drug zanzalintinib in 16 adults with recurrent or metastatic olfactory neuroblastoma, a rare cancer of the nasal cavity. The goal is to see if the drug can help control the disease and to check its safety. Participants must not have had prior treatment with similar drugs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT MD Anderson

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

zanzalintinib (a drug taken orally that targets blood vessel growth in tumors)

What this could lead to

If it works, this could offer a new treatment option to control recurrent or metastatic olfactory neuroblastoma, a rare cancer.

What could go wrong

This is a small, early-phase trial with only 16 participants, so results may not apply broadly. The drug may cause side effects or fail to control the cancer.

Conditions

The condition(s) this trial relates to.

esthesioneuroblastoma Esthesioneuroblastoma, Olfactory

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.