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Experimental cell therapy takes on lupus and scleroderma

NCT ID NCT06708845

First seen Jun 14, 2026 · Last updated Jun 14, 2026

Summary

This early-phase trial tests a new treatment called zamto-cel for people with severe lupus or scleroderma that hasn't improved with standard therapies. Zamto-cel uses a patient's own immune cells, modified to target and calm the overactive immune system. The main goal is to check safety and find the right dose, while also watching for any reduction in disease activity over a year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Froedtert Hospital and the Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Autoimmune Diseases Immune System Diseases Lupus Erythematosus, Systemic Lupus Nephritis Scleroderma, Diffuse Scleroderma, Systemic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.