CAR-T therapy takes on rare Muscle-Weakening disease
NCT ID NCT06704269
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times
Summary
This early-phase study tests a new treatment called YTB323, a CAR-T cell therapy, for people with generalized myasthenia gravis that hasn't improved with standard treatments. The goal is to see if it is safe and can help control the disease. About 15 participants will receive the therapy and be closely monitored for side effects and how well it works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-••••
Locations
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Novartis Investigative Site
RECRUITINGBordeaux, 33076, France
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Novartis Investigative Site
RECRUITINGBrest, 29200, France
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Novartis Investigative Site
RECRUITINGLille, 59037, France
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Novartis Investigative Site
RECRUITINGChiba, 2608677, Japan
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Novartis Investigative Site
RECRUITINGKyoto, 606-8507, Japan
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Novartis Investigative Site
RECRUITINGSheffield, South Yorkshire, S10 2JF, United Kingdom
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Novartis Investigative Site
RECRUITINGLondon, SE5 9RS, United Kingdom
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Univ Cali Irvine ALS Neuromuscular
RECRUITINGOrange, California, 92868, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wake Forest Univ School of Medicine
RECRUITINGWinston-Salem, North Carolina, 27157-1052, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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