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Body chemistry secrets: how your sex and genes process a common drug

NCT ID NCT06939608

First seen Jan 22, 2026 · Last updated May 23, 2026 · Updated 24 times

Summary

This study looked at how the drug yohimbine is processed in healthy young adults, focusing on differences between men and women and how a specific gene (CYP2D6) affects metabolism. 36 volunteers took a single low dose of yohimbine and caffeine, and researchers measured drug levels in their blood. The goal was to better understand how sex and genetics influence drug breakdown, not to treat any disease.

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Contacts and locations

Locations

  • University Medicine Greifswald, Institute of Pharmacology

    Greifswald, Mecklenburg-Vorpommern, 17489, Germany

Conditions

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