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New drug YL242 takes on advanced solid tumors in first human trial

NCT ID NCT07197827

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 39 times

Summary

This study tests a new drug called YL242, given alone or with other treatments, for adults with advanced solid tumors that have not responded to prior therapy. The main goals are to check safety and see if tumors shrink. About 424 participants will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AUS-101

    NOT_YET_RECRUITING

    Liverpool, New South Wales, 2170, Australia

    Contact

  • AUS-102

    RECRUITING

    Darlinghurst, Victoria, 2010, Australia

    Contact

  • AUS-103

    NOT_YET_RECRUITING

    Heidelberg, Victoria, 3084, Australia

    Contact

  • AUS-104

    NOT_YET_RECRUITING

    Fitzroy, Victoria, 3065, Australia

    Contact

  • AUS-105

    NOT_YET_RECRUITING

    Nedlands, Western Australia, 6009, Australia

    Contact

  • CN-301

    RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

    Contact

  • CN-302

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact

  • CN-303

    RECRUITING

    Harbin, Heilongjiang, 150081, China

    Contact

  • US-201

    NOT_YET_RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact

  • US-202

    RECRUITING

    Sarasota, Florida, 34232, United States

    Contact

  • US-203

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact

  • US-204

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • US-205

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • US-206

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

    Contact

  • US-207

    NOT_YET_RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

Conditions

The condition(s) this trial relates to.

colorectal cancer gastroesophageal junction adenocarcinoma hepatocellular carcinoma neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.