Herbal ointment may stop stomach bleeds from blood thinners
NCT ID NCT07339956
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if a Chinese herbal ointment (Yiwei Jiaohuang) can help stop stomach bleeding caused by blood thinners like aspirin or warfarin. About 60 adults will take the ointment daily for 2 weeks, and doctors will check their stool for hidden blood. The goal is to see if the ointment speeds up recovery compared to standard acid-reducing medication alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Oral therapy with at least one antiplatelet or anticoagulant agent, including: aspirin, clopidogrel, ticagrelor, prasugrel, warfarin, rivaroxaban, apixaban, edoxaban, dabigatran, etc.; * BARC stage 1 or 2; * Traditional Chinese Medicine pattern identified as phlegm-heat and blood stasis obstruction syndrome; * Age 18-90 years; * Signed informed consent. Exclusion Criteria: * Patients with gastrointestinal bleeding resulting in hemoglobin levels \<20 g/L and/or requiring hospitalization; * Gastrointestinal malignancies; * Cases where the source of occult blood cannot be distinguished, such as fresh bleeding from hemorrhoids; * Concurrent use of hemostatic traditional Chinese medicine preparations like Yunnan Baiyao; * Significant liver or kidney dysfunction, with ALT, AST, or serum creatinine exceeding three times the upper limit of normal; * Pregnant women, women planning pregnancy, or lactating women; * Individuals deemed unsuitable for this clinical trial by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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China-Japan Friendship Hospital
Beijing, China
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