New drug YH42946 targets Hard-to-Treat lung and solid tumors
NCT ID NCT06616766
First seen Nov 05, 2025 · Last updated May 23, 2026 · Updated 32 times
Summary
This study tests a new drug called YH42946 in people with advanced solid tumors (including lung cancer) that have certain gene changes (HER2 or EGFR). The main goals are to check safety, how the drug moves through the body, and whether it shrinks tumors. About 161 participants who have run out of standard options will take part.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Asan Medical Center, University of Ulsan
RECRUITINGSeoul, South Korea
Contact
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Chungbuk National University Hospital
RECRUITINGCheongju-si, North Chungcheong, 28644, South Korea
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Next Oncology Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Samsung Medical Center
RECRUITINGSeoul, 06351, South Korea
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Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, 03080, South Korea
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Severance Hospital, Yonsei University
RECRUITINGSeoul, 03722, South Korea
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The Catholic Univ. of Korea St. Vincent's Hospital
RECRUITINGSuwon, Gyeonggi-do, 16247, South Korea
Contact
Conditions
Explore the condition pages connected to this study.