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Yerba mate study hopes to brew better cholesterol numbers

NCT ID NCT06896175

Disease control Sponsor: Universidad Nacional de Caaguazu Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether the time of year yerba mate is harvested and how people drink it (as hot mate, cold tereré, or both) can improve cholesterol and fat levels in the blood. About 198 regular yerba mate drinkers in Paraguay will be assigned to different groups and have their cholesterol checked over 6 months. The goal is to see if these factors can help manage lipid disorders.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 198 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individuals of both sexes, between 18 and 60 years of age, residing in the country, who consume prepared yerba mate. 2. Consumers of mate or tereré and mate/terere who agree to consume the yerba mate samples provided by the research team, which will be masked from laboratory analysis. 3. Two weeks of abstinence from consuming prepared yerba mate, either as mate or tereré, prior to randomization for the trial. 4. Consume exclusively prepared yerba mate in the prescribed manner (quantity of yerba, frequency of consumption, and sips), either in its mate or tereré form independently, and for those who consume both forms daily. 5. Do not change the yerba mate consumer's usual diet or regular physical activity during the trial period. 6. Agree to know the laboratory results of the lipid profile only at the end of the trial (180 days after the start). Exclusion Criteria: 1. Individuals receiving lipid-lowering treatment at the start of the trial. 2. Consuming any other type of yerba mate not provided by the principal investigator. 3. Individuals requiring vitamins as a nutritional supplement. 4. Individuals taking thermogenic supplements. 5. Individuals consuming cooked mate. 6. Addiction to medicinal plants or herbs, both mate and tereré. 7. Individuals with a personal history of coronary artery disease.

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Conditions

The condition(s) this trial relates to.

inherited lipid metabolism disorder Lipid Metabolism Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipid metabolism disorders

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • UNCA

    RECRUITING

    Coronel Oviedo, Paraguay

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