Yeast powder boosts bathroom visits, study hints
NCT ID NCT06911177
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a daily supplement made from yeast cell walls can increase bowel movements in healthy adults who currently go once a day or less. 70 participants will take either the yeast supplement or a placebo for 28 days. Researchers will track stool frequency, digestion symptoms, and gut bacteria changes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- yeast mannan (a dietary supplement from yeast cell walls)
- What this could lead to
- If it works, this could offer a natural, over-the-counter option to help people with mild constipation have more regular bowel movements.
- What could go wrong
- This is a small, early-stage trial with only 70 people. The effect may be small or no better than placebo, and results may not apply to people with more severe constipation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults who report a stool frequency of ≤ 1 per day. * Able to provide written informed consent in English. * Willingness to consume 1 supplement (12 g of yeast mannans or control) daily for 28 days. * Willingness to maintain their usual diet and physical activity patterns throughout the study and refrain from the consumption of any yeast-based foods (e.g. Marmite or Vegemite) or yeast extract supplements. * Willing to comply with study procedures, including stool and urine colle Exclusion Criteria: * Stool frequency of \< 3 per week * Yeast allergy * Vegan dietary pattern * Self-reported kidney disease * Elite athletes or long-distance runners * Use of antibiotic drugs within 1 month of screening * Current use of laxatives or antidiarrheal medications * Use of other investigational products within 3 months of the screening * Previously or currently being treated for intestinal diseases or conditions, including irritable bowel disease (i.e., IBS-D or IBS-mixed), Crohn's disease, ulcerative colitis, celiac disease, or gastrointestinal cancer. * Previous gastrointestinal surgery (e.g., gastric bypass, fundoplication, bowel resection). * Current cancer treatment. * Currently pregnant.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Food Science and Human Nutrition
Gainesville, Florida, 32611, United States