Honey paste could melt artery plaque and lower cholesterol
NCT ID NCT07314775
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether Yangxin Dawayimixike Honey Paste can reduce carotid artery plaque and improve cholesterol in people with dyslipidemia. Over 400 participants will receive either the honey paste or a placebo for 12 months, with a one-year follow-up. The main goal is to see if the paste thickens the artery wall less and lowers the risk of heart problems.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Yangxin Dawayimixike Honey Paste
- What this could lead to
- If it works, this honey paste could help reduce carotid artery plaque and improve cholesterol levels, potentially lowering heart attack and stroke risk.
- What could go wrong
- This is an early-stage Phase 4 trial with no results yet. The treatment may not outperform placebo, and long-term safety is still being studied.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 422 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Meets the diagnostic criteria for Carotid Atherosclerotic Plaque (CAP); 2. Meets the diagnostic criteria for dyslipidemia; 3. Meets the TCM syndrome differentiation criteria for Qi Stagnation and Blood Stasis pattern; 4. Aged 18-75 years, both sexes eligible; 5. Vital signs stable, conscious with normal communication ability; 6. Subject voluntarily participates and signs the informed consent form. Exclusion Criteria: 1. Patients with severe cardiovascular diseases, including acute myocardial infarction, unstable angina, NYHA Class II-IV heart failure, severe arrhythmias, congenital heart disease, or severe valvular heart disease; 2. Patients with poorly controlled hypertension (systolic blood pressure ≥180 mmHg or diastolic blood pressure \>100 mmHg), severe cerebrovascular diseases, hemorrhagic or hematologic disorders, or malignant tumors; 3. Patients with hepatic dysfunction, defined as alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) levels exceeding twice the upper limit of normal, or renal insufficiency, defined as serum creatinine levels exceeding 1.5 times the upper limit of normal; 4. Patients with severe psychological disorders, intellectual disabilities, or language barriers; 5. Pregnant or lactating women; 6. Patients with known hypersensitivity to the investigational drug; 7. Patients concurrently participating in other clinical trials.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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