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Xenon anesthesia: nerve effects under the microscope in tiny trial

NCT ID NCT01043419

Knowledge-focused Sponsor: Air Liquide Santé International Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase study looked at whether xenon gas, used as anesthesia, changes the nerve signals that control muscles and blood pressure. Eight healthy volunteers received xenon gas for 30 minutes while researchers measured nerve activity, heart rate, and blood chemicals. The goal was simply to understand how xenon affects the body's automatic nervous system, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
xenon gas

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

8 people

The number who actually took part.

Start date

Jan 2010

Finished

Mar 2010

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy volunteers \> 18 years and \< 65 years of age * ASA physical status I * Legal competence * for whom the consent form has been signed Exclusion Criteria: * Healthy volunteers \< 18 years and \> 65 years of age * Pregnancy, lactation period or missing secure anticonvulsive therapy * Missing legal competence * Participation in other clinical trials * Contraindications as mentioned on §4.3 of the SPCs of LENOXe™ (xénon 100 % v/v) * Any medication especially of Sildenafil (Viagra®) or other potency remedy * Existing relationship of dependency to the sponsor or the investigator

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Conditions

The condition(s) this trial relates to.

sympathetic nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sympathetic nervous system

Contacts and locations

Locations

  • Department of Anesthesiology; University Hospital of Duesseldorf; Moorenstrasse 5

    Düsseldorf, 40225, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.