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New immune booster XB628 enters first human tests for tough cancers

NCT ID NCT06952010

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 34 times

Summary

This early-phase study tests a new drug called XB628 in about 75 people with advanced solid tumors that have not responded to standard treatments. XB628 is designed to help the body's natural killer cells attack cancer cells more effectively. The main goals are to find a safe dose and understand side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Exelixis Clinical Site #1

    RECRUITING

    Hickory, North Carolina, 28602, United States

  • Exelixis Clinical Site #10

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Exelixis Clinical Site #11

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Exelixis Clinical Site #2

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Exelixis Clinical Site #3

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Exelixis Clinical Site #4

    RECRUITING

    New Haven, Connecticut, 06520, United States

  • Exelixis Clinical Site #5

    RECRUITING

    San Francisco, California, 94158, United States

  • Exelixis Clinical Site #6

    RECRUITING

    St Louis, Missouri, 63108, United States

  • Exelixis Clinical Site #7

    RECRUITING

    New York, New York, 10029, United States

  • Exelixis Clinical Site #8

    RECRUITING

    Tampa, Florida, 33612, United States

  • Exelixis Clinical Site #9

    RECRUITING

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.