New study tests better pain control for common wrist breaks
NCT ID NCT07183904
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether adding a nerve block to a standard hematoma block reduces pain better during wrist fracture realignment. 180 adults with displaced wrist fractures were randomly assigned to receive either a hematoma block alone or a hematoma block plus a median nerve block. Pain was measured during the procedure and at discharge. The goal is to improve patient comfort during this common emergency procedure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mepivacaine
- What this could lead to
- If the combined block works better, it could lead to a new standard for pain control during wrist fracture reduction, making the procedure more comfortable for patients.
- What could go wrong
- This is a completed trial with 180 participants, but the results are not yet widely adopted. The benefit may be small, and nerve blocks carry rare risks like infection or nerve injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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180 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 100 years. * Diagnosis of acute displaced distal radius fracture (\< 48 hours since injury). * Indication for closed reduction and immobilization. * Ability to provide informed consent. Exclusion Criteria: * Age under 18 years or open physes on plain radiograph. * Open or pathological distal radius fractures. * Local infection at or near the planned injection site. * Significant neurological disease or cognitive impairment interfering with study participation. * Presence of osteosynthesis material in the same segment of the affected limb. * Known allergy or contraindication to local anesthetics used in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
12 de Octubre University Hospital
Madrid, Madrid, 28041, Spain