Could a simple wash cut C-Section infections?
NCT ID NCT06339203
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether washing the wound with a low-dose chlorhexidine solution after a C-section helps prevent infections and improves healing compared to standard saline. The trial will include 400 women at higher risk for complications, such as those with obesity or diabetes. Participants will be randomly assigned to receive either the chlorhexidine wash or saline during surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Chlorhexidine Gluconate (0.05%) in sterile water
- What this could lead to
- If it works, this could provide a simple, low-cost way to reduce wound infections and complications after C-section in high-risk women.
- What could go wrong
- This is a relatively small, early-stage trial (400 participants) and the results may not apply to all women. The chlorhexidine wash could cause irritation or allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 or older * Singleton pregnancy * Planned cesarean delivery at gestational age 37 weeks or later at Loma Linda University Children's Hospital * Planned post-operative follow up with Loma Linda OBGYN * Speak English or Spanish * At least one of the following medical complications: Obesity BMI\>= 30kg/m2, Diabetes, Spontaneous rupture of membranes, Intraamniotic infection Exclusion Criteria: * Emergency cesarean delivery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Loma Linda University
RECRUITINGLoma Linda, California, 92354, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could having a partner present during emergency C-Sections improve Mothers' mental health?
- When pain strikes during C-Section: what Women's stories reveal
- Which drug stops Post-Birth bleeding better? a Head-to-Head test