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New therapy helps veterans with mental illness find work and improve health

NCT ID NCT04504903

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a therapy called Cognitive Behavioral Therapy for Work Success (CBTw) in 294 veterans with serious mental illness (like depression, bipolar disorder, or PTSD) who were unemployed. The goal was to help them find and keep competitive jobs, which can improve their health and well-being. The therapy focused on changing unhelpful thoughts and behaviors related to work.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

294 people

The number who actually took part.

Started

Jan 2021

Finished

Sep 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Unemployment, defined as no current participation in a competitive job * A competitive work goal, which denotes a goal of a regular job in the community that pays at least minimum wage * Presence of a serious mental illness including one or more of the following conditions: * major depression * bipolar disorders * schizophrenia * schizoaffective disorder * posttraumatic stress disorder (PTSD) * Currently enrolled in and receiving VA vocational rehabilitation services Exclusion Criteria: * Previous participation in cognitive behavioral therapy intervention geared toward work * Presence of a severe medical or cognitive impairment that will prevent participation in the study

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Conditions

The condition(s) this trial relates to.

bipolar disorder major depressive disorder post-traumatic stress disorder schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Posttraumatic stress disorders

Contacts and locations

Locations

  • Edward Hines Jr. VA Hospital, Hines, IL

    Hines, Illinois, 60141-5000, United States

  • Richard L. Roudebush VA Medical Center, Indianapolis, IN

    Indianapolis, Indiana, 46202-2884, United States

  • St. Louis VA Medical Center John Cochran Division, St. Louis, MO

    St Louis, Missouri, 63106, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.