Brain training for HIV seniors: a first step
NCT ID NCT06699927
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tested whether a working memory training program is practical and acceptable for people aging with HIV. Researchers enrolled 100 participants aged 50-85, including those with and without HIV, to see if the training could improve memory and thinking skills. The goal was to gather information for future, larger studies, not to provide a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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100 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 50-85 years of age * Able to understand and speak English and follow study procedures * Does not have a psychological or neurological condition that would prevent being able to give consent to participate * Not currently involved in any other cognitive or memory training studies Exclusion Criteria: * Formal diagnosis of dementia or other neurological disease, including Mild cognitive impairment. * A final total score below 17 on Montreal Cognitive Assessment - Blind (telephone) version. * Score of 10 or more on the Generalized Anxiety Questionnaire (GAD7; Spitzer et al., 2006, Archives of Internal Medicine), indicating presence of moderate or severe anxiety * Score of 9 or more on Geriatric depression scale (GDS15; Yesavage et al., 1982) indicating presence of moderate or severe depression * Abnormal visual acuity prohibitive of tablet-based training. * Physical handicap (motor or perceptual) that would impede training procedures. * Medical illness requiring treatment and/or significant absences during the study timeline. * Current evidence or 2-yr history of seizures, focal brain lesion, or head injury with loss of consciousness. * Current alcohol consumption exceeds 14 drinks per week. * Self-reported illicit drug use.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Northeastern University
Boston, Massachusetts, 02115, United States
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Other studies related to the condition(s) this trial covers.
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