East meets west: can adding chinese herbs boost weight loss drugs?
NCT ID NCT07646457
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding Traditional Chinese Medicine (TCM) to standard weight-loss drugs helps people lose more weight. About 296 adults with obesity (BMI 27 or higher) in Taiwan are being followed for 6 to 12 months. Researchers are measuring weight loss, body fat, and muscle-to-fat ratio to see if the combination works better than drugs alone.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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296 people
The number who actually took part.
- Started
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Apr 2026
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with overweight or obesity receiving weight management treatment in a hospital-based outpatient setting in Taiwan. Participants were identified from a retrospective clinical database and received pharmacologic therapy, primarily semaglutide, with or without adjunctive medications and/or traditional Chinese medicine interventions.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥20 years * Obesity defined by Health Promotion Administration, Taiwan: BMI ≥27 kg/m², or BMI ≥24 kg/m² with metabolic comorbidities * Received weight management treatment * Primary pharmacologic therapy with: Rybelsus® (oral semaglutide), or Ozempic® (subcutaneous semaglutide) * May have received adjunctive weight-loss medications, including: Mounjaro® (tirzepatide), SGLT2 inhibitors, Contrave® (naltrexone/bupropion) Exclusion Criteria: * Incomplete data, including missing baseline measurements or absence of follow-up records, precluding assessment of treatment effectiveness * Pregnancy or breastfeeding * History of bariatric surgery during the study period (e.g., gastric bypass, gastric banding) * Presence of major medical conditions that may significantly affect body weight independent of obesity treatment (e.g., active malignancy, end-stage organ failure) * Patients deemed unsuitable for inclusion by the investigators (e.g., poor treatment adherence or unreliable data)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Yang Ming Chiao Tung University
Taipei, 112, Taiwan
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