Diet bars tested for weight loss and health boost in overweight adults
NCT ID NCT07165548
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether eating special protein and fiber bars three times a day, as part of a low-calorie diet, helps overweight or obese adults lose weight and improve heart and joint health. About 144 participants will be split into four groups, each receiving a different bar formula or a placebo bar. The trial lasts 12 weeks and measures weight, body composition, blood markers, and joint comfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- satiating protein and fiber bars
- What this could lead to
- If successful, this could offer a practical, food-based supplement to boost weight loss and improve heart and joint health in people with overweight or obesity.
- What could go wrong
- This is a small, early-stage study (144 participants) testing dietary supplements, not a drug. Results may not apply to everyone, and weight loss depends on strict diet adherence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 144 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Volunteers of both sexes between the ages of 18 and 65 years old. * Volunteers with grade II overweight or obesity (BMI: 27.0-39.9 kg/m2). * Physical examination and vital signs are normal or clinically irrelevant to the study. * Volunteers receiving pharmacological treatment may be included if the dosage has remained stable for at least three months prior to study initiation. * Individuals undergoing treatment for diabetes will be excluded. * Participants must be capable of understanding the study requirements, willing to provide written informed consent, and able to comply with all study procedures and timelines. * Body weight must have remained stable (±5%) during the three months preceding study initiation. Exclusion Criteria: * Presence of significant functional or structural abnormalities of the digestive system, including but not limited to congenital malformations, angiodysplasia, active peptic ulcer disease, chronic inflammatory or malabsorption disorders, hiatal hernia, or chronic gastroesophageal reflux. * High alcohol consumption, defined as \>14 units per week for women and \>20 units per week for men. * Pregnancy or lactation at the time of screening. * History of surgical procedures resulting in permanent alterations of the digestive system (e.g., gastroduodenostomy) or joint replacement surgery (hip or knee). * Diagnosis of arthritis. * History of any liver disease, with the exception of non-alcoholic fatty liver disease. * Diagnosis of any type of cancer, current cancer treatment, or history of cancer treatment within the past five years. * Known allergy or hypersensitivity to any component of the investigational product or to any food that could interfere with study participation and follow-up. * Presence of cognitive and/or psychological impairment that could affect study compliance. * Anticipated poor adherence or, in the opinion of the investigator, inability to comply with study procedures. * Engagement in night-shift work. * Current use of dietary supplements that may interfere with study outcomes (e.g., nutraceuticals containing compounds with potential weight loss effects). * Ongoing treatment for weight loss or diabetes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Center for Nutrition Research
RECRUITINGPamplona, Navarre, 31008, Spain
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