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New weight loss drug shows promise in early trial

NCT ID NCT07121153

First seen Feb 25, 2026 · Last updated Jun 23, 2026 · Updated 16 times

Summary

This study tested a new medicine called NNC0487-0111 for weight control in 36 Chinese adults with overweight or obesity. Participants received either the drug or a placebo injection. The main goal was to check safety and how the drug moves through the body. The trial lasted up to 53 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Jinan Central Hospital

    Jinan, Shandong, 250000, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NNC0487-0111

What this could lead to

If this drug is safe and works, it could offer a new option for weight management in people with overweight or obesity.

What could go wrong

This is an early Phase 1 trial with only 36 participants, so it's too soon to know if the drug is effective or safe long-term. Many drugs fail in early testing.

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.