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New Low-Dose combo after transplant aims to stop leukemia relapse

NCT ID NCT06129734

First seen Apr 28, 2026 · Last updated May 20, 2026 · Updated 5 times

Summary

This study tests whether a low-dose, weekly chemotherapy combination (decitabine and venetoclax) given after a stem cell transplant can prevent relapse in people with high-risk acute myeloid leukemia or myelodysplastic syndromes. About 20 participants will receive the treatment for up to one year, alongside standard post-transplant care. The main goals are to see if the approach is safe and feasible, and whether it helps control any remaining cancer cells with fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospitals Seidman Cancer, Case Comprehensive Cancer Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Email: •••••@•••••

Conditions

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