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New drug combo offers hope for head and neck cancer patients who Can't take standard treatment

NCT ID NCT04858269

First seen Oct 31, 2025 · Last updated Jun 16, 2026 · Updated 38 times

Summary

This study tests a weekly combination of chemotherapy (carboplatin and paclitaxel) plus immunotherapy (pembrolizumab) in 31 adults with advanced head and neck cancer that has spread. It is for patients who cannot take the standard drug 5-fluorouracil. The goal is to see if this regimen shrinks tumors better than immunotherapy alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Wake Forest Baptist Health Sciences

    Winston-Salem, North Carolina, 27157, United States

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms hypopharynx squamous cell carcinoma laryngeal squamous cell carcinoma metastatic squamous cell carcinoma oral cavity squamous cell carcinoma oropharynx squamous cell carcinoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.