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New combo therapy shows promise for Hard-to-Treat breast cancer

NCT ID NCT06612203

First seen Jan 04, 2026 · Last updated May 22, 2026 · Updated 19 times

Summary

This study tests a combination of two drugs, Debio 0123 and sacituzumab govitecan, in people with advanced breast cancer that has not responded to previous treatments. The goal is to find the safest dose and see if the combination can shrink tumors. About 76 participants will take part across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Barts Health NHS Trust

    London, United Kingdom

  • Beatson West of Scotland Cancer Center

    Glasgow, United Kingdom

  • Hospital Arnau de Vilanova de Valencia

    Valencia, Spain

  • Hospital Beata María Ana

    Madrid, Spain

  • Hospital Universitari Dexeus

    Barcelona, Spain

  • Hospital Universitario Clínico San Cecilio de Granada

    Granada, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, Spain

Conditions

Explore the condition pages connected to this study.