Could a water flosser beat plaque and gingivitis?
NCT ID NCT07204951
First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 3 times
Summary
This study tests whether a water flosser can improve oral health in adults with plaque-induced gingivitis. Sixty-four healthy adults will use the device twice daily after brushing. Researchers will measure changes in plaque and gum inflammation over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Water flosser device
- What this could lead to
- If effective, this water flosser could offer a simple, safe way to improve gum health and reduce plaque at home.
- What could go wrong
- This is a small, early-stage trial with only 64 people. Results may not apply to everyone, and the device may not be better than regular flossing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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64 people
The number who actually took part.
- Started
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Nov 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: 18 to 65 years (both inclusive) old at the time of consent. 2. Sex: Healthy adult males and non-pregnant/non-lactating females. 3. Females of childbearing potential have a self-reported negative urine pregnancy test at the time of the screening visit and agree to follow an accepted method of birth control for the duration of the study such as condoms, foams, jellies, diaphragm, intrauterine device etc. 4. Subjects are generally in good general health as determined from recent medical history. 5. Subjects with mild to moderate gingivitis and good oral health, without hard or soft tissue lesions, with moderate gingivitis characterized by more than 30% bleeding sites and probing depths of ≤3 mm without attachment loss. 6. Anterior teeth without restorations. 7. No dental treatments being performed before or during the study period. 8. Possessing at least 20 permanent teeth (excluding the third molars) and 5 evaluable teeth in each quadrant. 9. Subjects who agree to discontinue the use of over-the-counter any teeth products throughout the trial except for the ADA-approved toothbrush and toothpaste provided during the study. 10. Subjects who agree to refrain from the use of any other type of floss or similar dental product during the study. 11. Agree not to participate in any other oral/dental product studies during the trial. 12. Agree to return for all scheduled visits and follow study procedures. 13. Subjects who are willing to complete all study procedures including study-related questionnaires and comply with study requirements. Exclusion Criteria: 1. Subjects who are undergoing treatment for gingivitis, caries, dental plaque and sensitivity. 2. Subjects are present with fixed orthodontic appliances on the facial surfaces of the maxillary arch. 3. Subjects have dental crowns, veneers or composite restorations on gradable maxillary anterior teeth (canine to canine) or mandibular anterior teeth. 4. Subjects have any oral pathologies or gross neglect of home care requiring prompt treatment, including periodontal disease, as evidenced by purulent exudate, tooth mobility, and/or other signs indicating that the integrity of the data collected for that subject might be compromised. 5. Subjects are present with any pre-existing oral or medical condition that the Investigator/designee determines may place the subject at increased health risk from study participation. 6. Suffering from untreated dental caries, mucosal lesions, oral tumors or severe systemic diseases that may affect periodontal diseases. 7. Subjects have any known allergies to over-the-counter oral hygiene/products. 8. Subjects have any known allergies to the trial product ingredients. 9. The subject must have participated in a clinical study with oral care or oral hygiene within 4 weeks before the screening visit of this study. 10. Any other condition which could warrant exclusion from the study, as per the Investigator's discretion 11. Subjects who smoke and are pan eaters. 12. Subjects with hypersensitive teeth. 13. Subjects having chipped teeth and defective restorations. 14. Subjects having deep periodontal pockets. 15. Subjects having bridgework in their teeth and dentures which interrupt during evaluation. 16. Subjects undergoing treatment with antibiotics, anti-inflammatory, anticonvulsants, anti-histaminic, anti-depressant, anti-histaminic, sedatives, tranquilizers or daily analgesic drugs. 17. Subjects having uncontrolled metabolic disease. 18. Subjects' overexposure to acidic by dietary and environment exposure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NovoBliss Research
Ahmedabad, Gujarat, 382481, India
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Other studies related to the condition(s) this trial covers.
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