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Walk and think: new training may boost brain and body in Alzheimer's

NCT ID NCT06731049

Symptom relief Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding mental tasks to treadmill walking (dual-task training) improves movement, thinking, and daily living skills more than walking alone. It involves 46 people with early-to-mid stage Alzheimer's who can already walk. The goal is to see if this combined approach helps them function better in everyday life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 46 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Diagnosis of Alzheimer's disease according to the NINCDS-ADRDA criteria by a neurologist, 2. In the early or middle stages of the disease according to the Clinical Dementia Rating Scale (CDR), 3. Receiving medical treatment for Alzheimer's disease (e.g., cholinesterase inhibitors or memantine) for at least the past month, 4. Able to walk at least 400 meters in the 6-Minute Walk Test, indicating functional mobility, 5. Able to read and understand instructions given in Turkish. Exclusion Criteria: 1. Having Lewy body dementia, frontotemporal dementia, or other types of dementia 2. Participating in a structured exercise program within the 6 months prior to starting the study 3. Having pulmonary, neurological, musculoskeletal, or rheumatological diseases that hinder walking 4. Having an unstable medical condition (e.g., uncontrolled diabetes or hypertension, deep vein thrombosis, etc.) 5. Having visual or auditory impairments that make communication difficult 6. Having behavioral problems that make participation in exercise difficult

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia disease Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer' disease Dementia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • İstanbul University-Cerrahpaşa

    RECRUITING

    Istanbul, Turkey (Türkiye)

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