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New numbing cocktail may ease pain of central line insertion

NCT ID NCT07299383

Symptom relief Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special numbing mixture called WALANT could reduce pain during central venous catheter (CVC) insertion better than standard lidocaine. Sixty-four trauma or dialysis patients were randomly assigned to receive either WALANT or lidocaine before the procedure. Pain was measured using a visual scale. The goal was to see if WALANT offers a more comfortable and potentially safer alternative for this common but uncomfortable procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
WALANT solution (lidocaine, isotonic saline, sodium bicarbonate, epinephrine)
What this could lead to
If WALANT works better, it could offer a more comfortable and safer way to numb the area for central line placement, especially in patients at risk of bleeding.
What could go wrong
This is a small, completed study with only 64 participants. The results may not apply to all patients or settings, and the technique requires a 20-minute wait before the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

Jan 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who are over 18 years of age, not pregnant, have a Glasgow Coma Scale score of 15, are oriented and cooperative, and have a hemorrhagic shock stage of at most 1 or are not in hemorrhagic shock. Exclusion Criteria: * Patients who are younger than 18 years of age, pregnant, have \<15 points on the Glasgow Coma Scale, are not oriented or cooperative, are in hemorrhagic shock stage \>1, have coagulopathy, increased intracranial pressure, bleeding-obstruction-thrombus in the target vessel, skin infection in the relevant area, or have burns.

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Conditions

The condition(s) this trial relates to.

injury nutritional deficiency disease protein-energy malnutrition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dialysis catheter Malnutrition severe Trauma (including fractures)

Contacts and locations

Locations

  • Atatürk University Research Hospital

    Erzurum, Erzurum, 25240, Turkey (Türkiye)

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