New numbing cocktail may ease pain of central line insertion
NCT ID NCT07299383
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study tested whether a special numbing mixture called WALANT could reduce pain during central venous catheter (CVC) insertion better than standard lidocaine. Sixty-four trauma or dialysis patients were randomly assigned to receive either WALANT or lidocaine before the procedure. Pain was measured using a visual scale. The goal was to see if WALANT offers a more comfortable and potentially safer alternative for this common but uncomfortable procedure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atatürk University Research Hospital
Erzurum, Erzurum, 25240, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
WALANT solution (lidocaine, isotonic saline, sodium bicarbonate, epinephrine)
What this could lead to
If WALANT works better, it could offer a more comfortable and safer way to numb the area for central line placement, especially in patients at risk of bleeding.
What could go wrong
This is a small, completed study with only 64 participants. The results may not apply to all patients or settings, and the technique requires a 20-minute wait before the procedure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.