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Simple leg position change may reduce radiation burns in vulvar cancer

NCT ID NCT05014191

Symptom relief Sponsor: King Hussein Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether lying with legs straight or bent (frog-leg) during radiation therapy for vulvar cancer affects skin burns. Twenty women with early-stage vulvar cancer took part. The goal was to see which position causes fewer skin side effects and whether it shortens treatment time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
radiation therapy (VMAT) with positioning change
What this could lead to
If successful, this could show that a simple change in leg position during radiation reduces skin burns and treatment delays for vulvar cancer patients.
What could go wrong
This is a very small, single-center study with only 20 participants, so results may not apply to all patients. The benefit of positioning may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Jul 2020

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Women who were diagnosed with vulvar carcinoma, receiving adjuvant or definitive chemoradiation to primary disease and inguinal lymph nodes

Ages

18 to 80 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>= 18 years * ECOG PS = 0-1 * Women with Bx confirmed vulvar cancer FIGO stage I-IVA (treated with curative intent) Exclusion Criteria: * Patients whom radiotherapy plans do not cover inguinal lymph nodes will be excluded. Vulnerable patients will be excluded (pregnant)

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Conditions

The condition(s) this trial relates to.

radiation injury vulva cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Radiation toxicity

Contacts and locations

Locations

  • King Hussein Cancer Center

    Amman, Amman Governorate, 11941, Jordan

More trials for these conditions

Other studies related to the condition(s) this trial covers.