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New hope for PNH patients with persistent anemia: experimental drug VSA012 enters human testing

NCT ID NCT06848296

First seen May 08, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This early-stage study tests an investigational drug called VSA012 in about 50 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder. Participants either have not used complement inhibitors or still have low red blood cell counts despite prior treatment. The main goals are to check safety and see if the drug improves blood markers like LDH and hemoglobin.

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Contacts and locations

Locations

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, China

  • The First Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.