New eye disease treatment shows promise in major trial

NCT ID NCT06384547

Completed Disease control Sponsor: Viridian Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested the safety of an experimental drug called VRDN-001 for people with thyroid eye disease. The drug works by blocking a specific receptor to reduce inflammation and swelling around the eyes. The trial involved 231 participants and was designed to see how well people tolerated the treatment while also measuring changes in eye bulging.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

4 Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ

Wroclaw, 53-114, Poland
AP-HP - Hôpital de la Pitié Salpétrière

Paris, 75013, France
Advancing Research International, LLC

Los Angeles, California, 90023, United States
Advancing Research International, LLC

Las Vegas, Nevada, 89144, United States
Baylor College of Medicine (BCM) - Ophthalmology

Houston, Texas, 77030, United States
CH Nice

Nice, 06000, France
CHU d'Angers

Angers, 49100, France
Centre Hospitalier National D'ophtalmologie

Des Quinze Vingts Paris, 75012, France
Clinica Bonanova de Cirugia Ocular

Barcelona, 08022, Spain
Clinica Universidad de Navarra

Pamplona, 31008, Spain
Clínica Universidad de Navarra

Madrid, 28027, Spain
Cockerham Eye Consultants, PC

San Diego, California, 92108, United States
Complexo Hospitalario Universitario de Santiago-Hospital Médico-Cirúrxico de Conxo

Santiago de Compostela, A Coruña, 15706, Spain
Edward Jenner Research Group Center LLC

Plantation, Florida, 33317, United States
FOMAT Medical Research

Santa Maria, California, 93454, United States
Fraser Eye Care Center

Fraser, Michigan, 48026, United States
Guy's and St. Thomas NHS Trust

London, SE1 7EH, United Kingdom
Hospital Arruzafa

Córdoba, 14012, Spain
Hospital Universitario Ramón y Cajal

Madrid, 28034, Spain
Hospital Universitario Virgen De La Macarena, Servicio de Oftalmología

Seville, 41071, Spain
Johannes Gutenberg-University Medical Center

Mainz, 55131, Germany
KU Medical Center, University of Kansas

Kansas City, Kansas, 66103, United States
Kahana Oculoplastic & Orbital Surgery

Livonia, Michigan, 48152, United States
Massachusetts Eye and Ear

Boston, Massachusetts, 02114, United States
Med-Care Research Inc.

Miami, Florida, 33125, United States
Miguel Servet University Hospital, Clinical Trials Unit

Zaragoza, 50009, Spain
NZOZ E-Vita

Bialystok, 15-879, Poland
Neuro-Eye Clinical Trials

Houston, Texas, 77074, United States
Neuro-Ophthalmology of Texas, PLLC

Houston, Texas, 77074, United States
New York Eye Ear Infirmary of Mount Sinai

New York, New York, 10003, United States
North Shore Eye Surgery

Sydney, 2065, Australia
Northwick Park Hospital

London, HA1 3UJ, United Kingdom
Ophthalmic Consultants of Boston

Weymouth, Massachusetts, 02189, United States
Panstwowy Instytut Medyczny MSWiA

Warsaw, 02-507, Poland
Rutgers- New Jersey Medical School- Newark

Newark, New Jersey, 07103, United States
Santa Familia PTG Lodz

Lódz, 90-302, Poland
Sarasota Retina Institute

Sarasota, Florida, 34231, United States
Sina Medical Center LLC

Homestead, Florida, 33034, United States
Specjalistyczny Osrodek Okulistyczny Oculomedica

Bydgoszcz, 85-870, Poland
Stanford Byers Eye Institute

Palo Alto, California, 94303, United States
Sydney Eye Hospital

Sydney, 2000, Australia
United Medical Research Institute

Inglewood, California, 90301, United States
University Health Diabetes, Endocrinology & Nephrology Center

Kansas City, Kansas, 64108, United States
University of Colorado - Dept of Ophthalmology

Aurora, Colorado, 80045, United States
University of Minnesota, Department of Ophthalmology and Visual Neurosciences

Minneapolis, Minnesota, 55455, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
Universitätsmedizin Göttingen

Göttingen, 37075, Germany
Vision Medical Research Inc.

Orland Park, Illinois, 60462, United States
West Virginia University Eye Institute

Morgantown, West Virginia, 26506, United States
Western Eye Hospital, Imperial College NHS Trust

London, NW1 5QH, United Kingdom

Conditions

Explore the condition pages connected to this study.

THYROID EYE DISEASE