Could a TB vaccine shield healthcare workers from COVID-19?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult (≥18 years) * Male or female * Hospital personnel with expected high SARS-CoV-2 exposure * Subject is contractually capable, able to understand information on study and has signed informed consent sheet * Subject has access to an internet-enabled electronic device * Women of childbearing potential who are currently using reliable methods of birth control, have a negative pregnancy test during screening and have no intention to become pregnant for at least 3 months post-vaccination. Exclusion Criteria: * Known hypersensitivity or allergy to (components of) the VPM1002 vaccine or serious adverse reactions to prior BCG administration * Known active or latent Mycobacterium tuberculosis infection or with another mycobacterial species. A history with or suspicion of M. tuberculosis infection. * Fever (\>38 °C) within the past 24 hours * Pregnant or breast-feeding * Suspicion of active viral or bacterial infection * Participation of subject in another study within 30 days before screening and during this study * Person is an employee of the sponsor, a relative of the investigator or in direct reporting line to clinical trial staff at the clinical trial site * Severely immunocompromised subjects, such as: 1. subjects with known infection with the human immunodeficiency virus (HIV); 2. subjects with solid organ transplantation; 3. subjects with bone marrow transplantation; 4. subjects under chemotherapy, immunotherapy and radiotherapy; 5. subjects with primary immunodeficiency; 6. treatment with any anti-cytokine therapies; 7. treatment with oral or intravenous steroids defined as daily doses of 10 mg prednisone or equivalent for longer than 3 months * Active solid or non-solid malignancy or lymphoma in the past 5 years * Direct involvement in the design or the execution of the present clinical trial * Expected absence from work of ≥4 of the following 12 weeks due to any reason (holidays, maternity leave, retirement, planned surgery etc) * Employed to the hospital \< 22 hours per week * Previous positive SARS-CoV-2 test result