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New imaging technique reveals how laryngectomy patients produce substitute voice

NCT ID NCT05561920

Knowledge-focused Sponsor: Osijek University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how people who had their voice box removed due to throat cancer produce a new voice. Researchers used a special high-speed camera to record vibrations in the throat and compared them to sound recordings. The goal was to better understand these substitute voices to improve speech therapy and quality of life for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

55 people

The number who actually took part.

Started

Aug 2022

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

adult male laryngectomised patients who completed oncological treatment and underwent voice rehabilitation

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * laryngectomised patients who completed minimal their 6-month period without disease after surgery and post-operative treatments such as radiotherapy or chemotherapy * patients with preserved reading skills * regular presence at follow-up visits Exclusion Criteria: * age less than 18 years * acute respiratory infection of the upper or lower respiratory tract * other primary cancer in the upper aerodigestive tract or lung * presence of neurologic or pulmonary diseases

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Conditions

The condition(s) this trial relates to.

laryngeal carcinoma laryngeal neoplasm larynx cancer Speech

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laryngectomy; status Larynx cancer

Contacts and locations

Locations

  • University Hospital Osijek

    Osijek, 31000, Croatia

More trials for these conditions

Other studies related to the condition(s) this trial covers.