Your voice may reveal hidden airway risks before surgery
NCT ID NCT07278232
First seen Jun 24, 2026 · Last updated Aug 25, 2026 · Updated 3 times
Summary
This study explores whether the sound of your voice can help doctors predict if placing a breathing tube during surgery will be difficult. Researchers will record 300 patients saying vowel sounds before surgery and use machine learning to find voice patterns linked to airway anatomy. The goal is to create a quick, non-invasive screening tool to improve patient safety.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple, painless voice test to help doctors identify patients who may have a difficult airway before surgery.
- What could go wrong
- This is an early observational study with only 300 participants, so results may not apply to everyone. The voice patterns might not reliably predict difficult intubation in practice.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients of 15-70 years scheduled for elective general anesthesia with tracheal intubation
- Ages
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15 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients scheduled for elective general anesthesia with tracheal intubation. Exclusion Criteria: * Patients with speech and pronunciation disorders (vocal cord diseases, cleft palate, craniofacial deformities, extensive tooth defects, cleft lip). * Hearing impairment (difficulty in communication, inaccurate repetition). * Patients with central nervous system diseases causing significant pronunciation abnormalities. * Patients contraindicated for direct laryngoscopy (e.g., post-chemotherapy in the pharynx, diseases prone to mucosal bleeding, etc.) that affect group allocation, as well as those unable to complete the recording or temporarily reassigned to other anesthesia methods.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shanghai Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine
RECRUITINGShanghai, China
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Other studies related to the condition(s) this trial covers.
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- Ultrasound may outshine old methods in predicting tough airways
- Can a little extra oxygen save tiny lungs during intubation?