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Experimental combo for tough blood cancers shows early promise but study halted

NCT ID NCT04702425

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 26 times

Summary

This early-phase study tested two experimental drugs, VOB560 and MIK665, together in 37 people with relapsed or refractory non-Hodgkin lymphoma, acute myeloid leukemia, or multiple myeloma. The goal was to find safe doses and see if the combination could kill cancer cells by blocking proteins that protect them. The study was terminated early, so final results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Ghent, 9000, Belgium

  • Novartis Investigative Site

    HUS, FIN-00029, Finland

  • Novartis Investigative Site

    Hong Kong, Hong Kong

  • Novartis Investigative Site

    Tel Aviv, 6423906, Israel

  • Novartis Investigative Site

    Rozzano, MI, 20089, Italy

  • Novartis Investigative Site

    Sunto Gun, Shizuoka, 411 8777, Japan

  • Novartis Investigative Site

    Seoul, 03080, South Korea

  • Novartis Investigative Site

    Santander, Cantabria, 39008, Spain

  • Uni of TX MD Anderson Cancer Cntr UT MD Anderson Cancer Ctr

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.