New drug duo targets Hard-to-Treat blood cancers

NCT ID NCT04702425

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 24 times

Summary

This study tested two experimental drugs, VOB560 and MIK665, given together to people with certain blood cancers (non-Hodgkin lymphoma, acute myeloid leukemia, or multiple myeloma) that had come back or stopped responding to treatment. The main goals were to find safe doses and see if the combination could shrink tumors. The study was stopped early, so results are limited.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Ghent, 9000, Belgium

  • Novartis Investigative Site

    HUS, FIN-00029, Finland

  • Novartis Investigative Site

    Hong Kong, Hong Kong

  • Novartis Investigative Site

    Tel Aviv, 6423906, Israel

  • Novartis Investigative Site

    Rozzano, MI, 20089, Italy

  • Novartis Investigative Site

    Sunto Gun, Shizuoka, 411 8777, Japan

  • Novartis Investigative Site

    Seoul, 03080, South Korea

  • Novartis Investigative Site

    Santander, Cantabria, 39008, Spain

  • Uni of TX MD Anderson Cancer Cntr UT MD Anderson Cancer Ctr

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.