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New study tests if vaginal surgery lowers brain pressure during hysterectomy

NCT ID NCT07250178

First seen Jan 06, 2026 · Last updated Jun 22, 2026 · Updated 24 times

Summary

This study compared two types of hysterectomy surgery: vNOTES (done through the vagina) and total laparoscopic hysterectomy (done through small belly cuts). Researchers measured the thickness of the optic nerve sheath, which can indicate pressure inside the skull. The goal was to see if vNOTES causes less pressure change. The study involved 66 patients and has been completed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

    Diyarbakır, Outside of the US, 21070, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If vNOTES is shown to reduce intracranial pressure changes, it could lead to safer hysterectomy options with fewer complications.

What could go wrong

This is a small, completed study using an indirect measure of intracranial pressure, so results may not confirm real clinical benefits or apply to all patients.

Conditions

The condition(s) this trial relates to.

endometrium neoplasm Metrorrhagia myofibroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.