Please sign in to follow a disease.
Can a tiny implant tame glaucoma? a feasibility trial puts the VW-50 to the test
NCT ID NCT07730424
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This study tests a new device called the VW-50, a small implant designed to drain fluid from the eye and lower pressure in people with glaucoma. The trial will enroll 10 adults whose eye pressure remains high despite medication. Surgeons will implant the device and rate how easy it is to place, while researchers track safety and pressure changes over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a surgical implant called VW-50 that drains fluid from the eye to lower pressure
- What this could lead to
- If it works, this could offer a new surgical option for people with glaucoma whose eye pressure is not controlled by medication.
- What could go wrong
- This is a very early feasibility study with only 10 participants, so it is too small to prove safety or effectiveness. The implant is new and has not been tested in humans before.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
10 people
The number who actually took part.
- Started
-
Aug 2022
- Finished
-
Oct 2023
- Lead sponsor
-
A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age - greater than 18 years of age. * Glaucoma - as diagnosed by the investigator based upon untreated intraocular pressure, disc appearance, and visual field abnormalities. * Failed medical treatment - In the opinion of the investigator, the IOP is uncontrolled in the study eye after having failed previous medical treatment. * Conjunctival health - In the opinion of the investigator the participant should have a healthy, free, and mobile conjunctiva in the target quadrant. * Capable - Ability to understand and willingness to follow study instructions and is likely to complete all required visits and procedures. Key Exclusion Criteria: * Prior glaucoma surgery in the study eye. * Advanced glaucomatous optic nerve damage which, in the opinion of the investigator, threatens fixation and/or standard surgery would be considered safer. * Active neovascular glaucoma, Iridocorneal Endothelial (ICE) Syndrome, traumatic glaucoma, silicone oil induced glaucoma, active acute angle closure glaucoma or subluxation of the lens. * Active diabetic retinopathy, choroidal neovascularization, branch retinal vein occlusion, central retinal vein occlusion, proliferative retinopathy, or other ophthalmic disease or disorder in the study eye that could confound study results. * Any condition of the cornea that could confound study results or would preclude accurate readings with an applanation tonometer and/or a contact pachymeter. * Visually significant cataract in the study eye that will not be removed at the time of implantation. * BCVA worse than 6/30 (Snellen equivalent) * Clinically significant inflammation or infection in either eye * Unfit for local anaesthetic surgery. * Any uncontrolled systemic disease. * Female participants who are pregnant, nursing, or planning a pregnancy during the study, or who are of childbearing potential and not using a reliable means of contraception during the study. * Significant risk of bleeding.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Glaucoma are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Melbourne Eye Specialists
Fitzroy, Victoria, 3065, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can exercise shield the eyes of glaucoma patients?
- Can better Follow-Up schedules save sight in glaucoma?
- Portable devices could take the guesswork out of eye pressure checks
- Eye drops may shield the cornea after cataract surgery
- Can a puff of air replace the eye pressure probe?
- New eye scans may catch glaucoma before vision loss