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Could vitamin d help heart surgery patients recover better?

NCT ID NCT04986033

Knowledge-focused Sponsor: Yonsei University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 135 adults having off-pump coronary artery bypass surgery to see if vitamin D levels affect hemoglobin (a protein in red blood cells) recovery after surgery. Researchers measured vitamin D and a hormone called hepcidin, which controls iron use. The goal was to understand why many patients develop anemia after heart surgery and whether vitamin D plays a role.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand why some patients develop anemia after heart surgery and point to vitamin D as a potential way to improve recovery.
What could go wrong
This is an observational study, not a treatment trial. It only looks for links between vitamin D and hemoglobin, so it won't prove that giving vitamin D helps. Results may not apply to all heart surgery patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

135 people

The number who actually took part.

Started

Aug 2021

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who consented to study enrollment among patients scheduled for off-pump coronary artery bypass graft

Ages

20 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Patients over 20 years of age undergoing off-pump coronary artery bypass graft Exclusion Criteria: 1. Emergency operation 2. Minimal invasive coronary artery bypass graft 3. Cooperative operation with other surgery 4. Patients who need a mechanical ventricular assist device 5. Patients with chronic kidney disease (eGFR \< 30) 6. Patients who have a end stage renal disease and need a hemodialysis 7. Patients with a low hemoglobin (Hb \< 10) before surgery 8. Patients who have a some disease(leukemia, myeloma, aplastic anemia, sickle cell anemia, etc) affecting hematopoiesis 9. Patients with a liver cirrhosis 10. Patients who receive vit. D, iron supplements, erythropoietin within 6 months 11. Patients who cannot understand the informed consent (eg. Foreigner, patients with cognitive dysfunction, etc) 12. Patients who disagree this study

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease

Contacts and locations

Locations

  • Division of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine, Cardiovascular Hospital, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea

    Seoul, South Korea

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