Vitamin d shows promise for Kids' bladder issues
NCT ID NCT06489951
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether high-dose vitamin D plus behavioral therapy can help children with dry overactive bladder (OAB) urinate less often. 180 children received either standard drugs or vitamin D drops for a short time. The goal was to see if vitamin D works better than usual medication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- vitamin D (dietary supplement)
- What this could lead to
- If it works, this could offer a simple, non-drug option to reduce frequent urination in children with dry overactive bladder.
- What could go wrong
- This is a small, completed trial with 180 children. The results may not apply to all kids, and high-dose vitamin D can have side effects like high calcium levels.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
180 people
The number who actually took part.
- Started
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Dec 2024
- Finished
-
Jul 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
5 to 18 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Children older than 5 years who were admitted to the Department of Urology, Children's Hospital Affiliated to Chongqing Medical University and diagnosed with dry OAB. 2. The results of our laboratory indicated that the serum vitamin D level was lower than 35ng/mL. 3. The child (guardian) has been informed of the nature of the study, understands the provisions in the protocol, is able to guarantee compliance, and signs the informed consent. Exclusion Criteria: 1. Patients with other urinary system malformations or serious diseases (such as hypospadias, cryptorchidism, posterior urethral valvular disease, vesicoureteral reflux, neurogenic bladder, urinary system tumors, urinary calculi, bladder and urethral injuries, etc.); 2. complicated with neurological diseases (such as epilepsy, spinal cord injury, spinal cord dysplasia, tethered cord syndrome, multiple sclerosis, autism spectrum disorder, etc.); 3. Patients with severe heart disease, abnormal liver and kidney function, lung disease, bone malformation, severe digestive tract disease, and genetic metabolic disease; 4. History of gastrointestinal surgery and urinary system surgery; 5. Dry stool, long-term constipation; 6. are taking anticonvulsant and antiepileptic drugs, hormones, antituberculosis drugs; 7. Previous history of hypercalcemia, hyperphosphatemia with renal rickets; 8. History of unexplained hematuria and urinary tract infection in the past 1 year; 9. Have a history of allergy or allergic reaction to vitamin D preparations; 10. Participating in another clinical study at the time of visit or during the follow-up of another clinical study; 11. Those who did not want to participate in the study or had poor follow-up compliance
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children's Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 400000, China
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