Can vitamin d help control diabetes? new trial tests high doses
NCT ID NCT07321223
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two different doses of vitamin D supplements in 108 adults with type 2 diabetes who also have low vitamin D levels. Researchers will measure changes in blood sugar and HbA1c over time to see if higher doses improve diabetes control. Participants must be aged 40-70 and taking only metformin.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin D
- What this could lead to
- If it works, this could show that correcting vitamin D deficiency helps control blood sugar in type 2 diabetes.
- What could go wrong
- This is a small, early-stage trial with no placebo group, so results may not be conclusive. Vitamin D is generally safe, but high doses can cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 108 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2024
- Expected to finish
-
Feb 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients diagnosed of T2DM with the age of 40-70 years from both genders taking only metformin with an Hb1Ac range of 7.5-9% and 25-hydroxy Vitamin D levels (25\[OH\]D) \<20ng/ml. Exclusion Criteria: Individuals Exclusion Criteria: Individuals with the following conditions will not be included as participants; * Inability or unwilling to participate or Clinical proximal myopathy * Renal, hepatic, endocrinological disorders or malignancies on basis of history * Serum calcium levels \> 10.5mg/dl * Use of insulin or any change in dosage of current hypoglycemic medications during last 3 months * Intake of vitamin D, calcium or omega 3 supplements within the past 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
PAF Hospital
Islamabad, Pakistan
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