Vitamin c: a simple shield against Surgery-Linked UTIs?
NCT ID NCT05913180
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking a daily vitamin C pill for 10 days can prevent catheter-associated urinary tract infections in women having elective gynecologic surgery. Half of the 180 participants will receive vitamin C, and half will receive a placebo. The goal is to see if this simple, low-cost approach reduces the number of infections.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin C (ascorbic acid) 1000 mg daily
- What this could lead to
- If it works, this could offer a simple, low-cost way to prevent urinary tract infections after gynecologic surgery, reducing antibiotic use.
- What could go wrong
- This is a small phase 2 trial, so results may not be conclusive. Vitamin C may not prevent infections effectively, and some people may experience side effects like stomach upset or kidney stones.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2023
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Nonpregnant women * 18 years of age or older * Undergoing elective GYN surgery Exclusion Criteria: * Pregnant women * Already taking Vitamin C supplementation * Nephrolithiasis * Congenital anomaly or neurogenic bladder * Allergy to ascorbic acid * On therapeutic anticoagulant medicine during the 6 weeks after surgery * Gynecological surgery involving fistula repair or a vaginal mesh removal * Positive Urinalysis in the pre-admission unit * Recurrent UTIs * Diabetes * G6PD * Hemochromatosis * Renal disorders
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Moscow State University of Medicine and Dentistry
RECRUITINGMoscow, Russia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which catheter holder is best? new study aims to reduce pain and infections
- Learning to avoid infections: study tests education for catheter patients