Could vitamin c help kids with severe pneumonia go home sooner?
NCT ID NCT07414693
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving vitamin C alongside standard hospital care can help children under five with severe pneumonia recover faster. Ninety children will be split into two groups: one gets standard treatment alone, the other gets standard treatment plus a daily dose of vitamin C. Researchers will compare how long each group stays in the hospital to see if vitamin C makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin C (ascorbic acid)
- What this could lead to
- If it works, this could offer a simple, low-cost way to speed recovery and shorten hospital stays for young children with severe pneumonia.
- What could go wrong
- This is a small, early-phase trial with only 90 children. The benefit of vitamin C for pneumonia is not yet proven, and results may not apply to all children.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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2 to 59 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * presenting with severe pneumonia * ≤ 48-hours duration Exclusion Criteria: * Congenital heart disease * Children with chronic respiratory illnesses i.e. Asthma, post tuberculosis bronchiectasis and cystic fibrosis * Immunosuppressed i.e. primary immune deficiency, malignancy, on steroid therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Children Hospital and Institute of Child Health
RECRUITINGMultan Khurd, Punjab Province, 60000, Pakistan
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