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Vitamin c trial aims to boost quality of life in lung cancer patients

NCT ID NCT05849129

Symptom relief Sponsor: The Canadian College of Naturopathic Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding intravenous vitamin C to standard chemotherapy can improve quality of life for people with advanced non-small cell lung cancer. About 90 adults with incurable lung cancer will receive either vitamin C or a placebo alongside their usual treatment. The main goal is to see if vitamin C helps reduce side effects and improve how patients feel.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Oct 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults (≥18 years of age) seen at TOHCC with stage IIIB or IV primary non-small cell lung cancer 2. Eligible and scheduled for first line platinum-doublet chemotherapy with or without concurrent immunotherapy Exclusion Criteria: 1. ECOG status greater than 2 2. Previously received IVC within 6 months prior to randomization 3. Biochemical deficiency in G6PD 4. Estimated Glomerular Filtration Rate (eGFR) less than 45 mL/min 5. Currently taking insulin or warfarin 6. History of severe renal dysfunction or hemochromatosis 7. Previously undergone cytotoxic chemotherapy or immunotherapy within 12 months prior to randomization 8. If pregnant or planning to become pregnant: not a carrier of the gene for G6PD deficiency 9. Currently taking an investigational product or participation in an investigational study within the past 30 days 10. Any reason which, under the discretion of the Principal Investigator or delegate, would preclude the patient from participating

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, K1H8L6, Canada

More trials for these conditions

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