Vitamin c shows promise in preventing Post-Fracture pain syndrome
NCT ID NCT05842395
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether taking vitamin C can prevent Complex Regional Pain Syndrome (CRPS), a painful condition that can develop after a wrist fracture. Researchers enrolled 220 adults with specific types of wrist fractures and gave them vitamin C to see if it reduced their risk. The goal was to find a simple, safe way to prevent this complication.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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220 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * participants who were injured with distal radius fractures and classified using the AO classification as A1, A2, A3, B1, and C1. Exclusion Criteria: * Multiple trauma patients. * patients who have neurovascular injuries. * Patients with fractures are classified using the AO classification as B2, B3, C2, and C3. * Patients who are eligible for open reduction internal fixation of their fractures. * Patients with chronic or acute renal failure. * Patients who already take multi-vitamin supplementation or vitamin C supplementation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Damascus University
Damascus, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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