Vitamin c IV may curb blood loss in hysterectomy
NCT ID NCT07335432
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving vitamin C through an IV before and during a hysterectomy can reduce blood loss. Forty women with fibroids or adenomyosis will receive either vitamin C or a placebo. Researchers will measure blood loss during surgery and check if vitamin C helps maintain blood counts and shorten hospital stays.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin C (ascorbic acid)
- What this could lead to
- If it works, this could point toward a simple, low-cost way to reduce bleeding during hysterectomy.
- What could go wrong
- This is a very small, early-stage trial with only 40 participants. The effect may be small or not clinically meaningful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female patients who underwent total abdominal hysterectomy * No bleeding tendency. * No history of anticoagulant or thrombolytic drug use * No contraindications to vitamin C supplementation Exclusion Criteria: * Inability to communicate in the Thai language. * Underwent total abdominal hysterectomy due to gynecologic malignancy. * Required emergency total abdominal hysterectomy. * History of vitamin C supplementation within 2 weeks prior to surgery. * History of smoking. * Previous abdominal surgery, such as bowel surgery, cesarean section
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Queen Savang Vadhana Memorial hospital
Si Racha, Changwat Chon Buri, 20110, Thailand
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI learn to spot endometriosis and fibroids on ultrasound?
- Sound waves vs. uterine pain: can HIFU calm adenomyosis?
- Uterine scar tissue after fibroid surgery: who is at risk?
- Can a water barrier make microwave ablation safer for the womb?
- A simple diet and muscle relaxant may sharpen views in scarless hysterectomy
- Could a fibroid drug help women with adenomyosis finally achieve a live birth?