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New drug VIS171 enters human testing for lupus, hair loss, and kidney disease

NCT ID NCT06799520

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 32 times

Summary

This early-stage trial tests a new drug, VIS171, in 30 people with lupus, alopecia areata, or a kidney condition called FSGS. The main goal is to check safety and how the body handles the drug. Participants receive VIS171 as a shot under the skin, alongside their usual care, and are followed for up to a year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Visterra Investigational Site

    RECRUITING

    Sofia, 1404, Bulgaria

  • Visterra Investigational Site

    RECRUITING

    Chisinau, MD-2025, Moldova

  • Visterra Investigational Site

    RECRUITING

    Bucharest, 11658, Romania

  • Visterra Investigational Site

    RECRUITING

    Cluj-Napoca, 40006, Romania

  • Visterra Investigational Site

    NOT_YET_RECRUITING

    Barcelona, 8035, Spain

  • Visterra Investigational Site

    NOT_YET_RECRUITING

    Granada, 18014, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VIS171

What this could lead to

If safe and effective, VIS171 could become a new treatment option for certain autoimmune diseases like lupus and alopecia areata.

What could go wrong

This is a very early Phase 1 trial with only 30 people, focused on safety. It is too soon to know if VIS171 works, and side effects are possible.

Conditions

The condition(s) this trial relates to.

alopecia areata systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.