New drug VIS171 enters human testing for lupus, hair loss, and kidney disease

NCT ID NCT06799520

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This early-stage trial is testing a new drug called VIS171 in 30 people with autoimmune diseases like lupus, alopecia areata, or a kidney condition called FSGS. The main goal is to see if the drug is safe and tolerable when given as a shot under the skin. Researchers will also look at how the drug affects immune cells in the blood.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Visterra Investigational Site

    RECRUITING

    Sofia, 1404, Bulgaria

  • Visterra Investigational Site

    RECRUITING

    Chisinau, MD-2025, Moldova

  • Visterra Investigational Site

    RECRUITING

    Bucharest, 11658, Romania

  • Visterra Investigational Site

    RECRUITING

    Cluj-Napoca, 40006, Romania

  • Visterra Investigational Site

    NOT_YET_RECRUITING

    Barcelona, 8035, Spain

  • Visterra Investigational Site

    NOT_YET_RECRUITING

    Granada, 18014, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VIS171

What this could lead to

If safe and effective, VIS171 could offer a new treatment option for autoimmune diseases like lupus, alopecia areata, and certain kidney conditions.

What could go wrong

This is a very early Phase 1 trial with only 30 participants, so it is primarily testing safety. It may not show clear benefit, and side effects are unknown.

Conditions

The condition(s) this trial relates to.

alopecia areata systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.