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Virtual-Reality bike plus brain zaps may boost arm movement in kids with cerebral palsy

NCT ID NCT04101994

Symptom relief Sponsor: Chang Gung Memorial Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether combining virtual-reality cycling training with noninvasive brain stimulation could improve upper limb motor function in 36 children and young adults with cerebral palsy. Participants used a virtual-reality bike while receiving either repetitive transcranial magnetic stimulation or transcranial electric stimulation. The goal was to see if these add-ons could enhance muscle strength and coordination beyond cycling alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
virtual-reality cycling training, repetitive transcranial magnetic stimulation, and transcranial electric stimulation
What this could lead to
If successful, this approach could offer a new, engaging way to improve arm and hand function in children with cerebral palsy.
What could go wrong
This is a small, early-stage study with only 36 participants. The effects may be modest or not last long, and brain stimulation can cause mild discomfort or headache.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Jun 2018

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 to 20 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of CP according to clinical criteria * Age 5-20 years * No use of botulinum toxin in the past 4 months * No significant perceptual or communication disturbances * No other peripheral or central nervous system dysfunction * No active inflammatory or pathologic changes in upper limb joints during the previous 6 months * No active medical problems, such as pneumonia, upper gastrointestinal bleeding, or urinary tract infection * No active problems of epilepsy and EEG without epileptiform discharge Exclusion Criteria: * Metabolic disorders, such as inborn error of metabolism, electrolyte, and endocrine disorders * Active infectious disease, such as meningitis and encephalitis * Patients with active medical problems, such as pneumonia, upper gastrointestinal bleeding, or urinary tract infection * Poor compliance or intolerance for the TMS therapy * Subjects with metallic implants or pregnancy. * EEG show epileptiform discharge * Patients with family history of epilipsy * Patients with symptoms that are restricted from tDCS, such as epilepsy, migraine and unstable health condition

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Conditions

The condition(s) this trial relates to.

cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy

Contacts and locations

Locations

  • Chang Gung Memorial Hospital

    Taoyuan, Taoyuan, 333, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.