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New imaging study aims to unlock secrets of human movement

NCT ID NCT00051857

Knowledge-focused Sponsor: National Institutes of Health Clinical Center (CC) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 01, 2026 · Updated 11 times

Summary

This study uses MRI and ultrasound to watch how muscles, tendons, and bones work together when you move. Researchers hope to learn what normal and injured movement looks like, which could lead to better ways to diagnose and treat problems like knee pain. Healthy volunteers and people with joint issues ages 5 to 95 can join.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could lead to better diagnostic tools and treatments for movement disorders like patellofemoral pain syndrome.
What could go wrong
This is an observational imaging study, not a treatment trial. It is early-stage and may not directly result in new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 750 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2003

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be primarily recruited from the greater Washington DC area.

Ages

5 to 95 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: Affected Participants: * Must be between the ages of 5-95 years. * Minors \< 18 years of age, they must be capable of providing assent (verbal or written) with parental or legal guardian permissions obtained. * Adults 18 \>= years of age, they must be able to provide informed consent. * Have the presence of a bone, muscle, soft tissue, connective tissue injury, impairment or related muscular skeletal system pathology. * Ability to have an MRI Scan. Healthy Volunteer Participants * Must be between the ages of 5-95 years. * Minors \< 18 years of age, they must be capable of providing assent (verbal or written) with parental or legal guardian permissions obtained. * Adults 18 \>= years of age, they must be able to provide informed consent. * Ability to have an MRI Scan. EXCLUSION CRITERIA: Affected Participants: -For the MR imaging portion of this study, all participants must complete the NIH Diagnostic Radiology screening questionnaire. If any potential contraindication is found, either the volunteer s doctor (with knowledge of the potential contraindication) or the radiology department at the NIH will be contacted to determine if the potential contraindication would exclude them from the specific MR scans being proposed. Healthy Volunteer Participants * Any relevant medical problems * Clinical signs of an impairment in the joint/limb being studied. * Any serious injury to the joint/limb being studied, previous surgery on the joint/limb being studied or extreme pain at the joint/limb being studied. * Neurologic Pathology affecting the muscular skeletal system * For the MR imaging portion of this study, all participants must complete the NIH Diagnostic Radiology screening questionnaire. If any potential contraindication is found, either the volunteer s doctor (with knowledge of the potential contraindication) or the radiology department at the NIH will be contacted to determine if the potential contraindication would exclude them from the specific MR scans being proposed.

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Conditions

The condition(s) this trial relates to.

Congenital Abnormalities patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abnormalities Imaging Patellofemoral pain syndrome

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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