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Ear zap for IBD? tiny study tests nerve stimulation for gut relief

NCT ID NCT07636304

First seen Jun 17, 2026 · Last updated Jun 22, 2026 · Updated 1 time

Summary

This pilot study tests whether daily, at-home stimulation of a nerve in the ear can change brain activity in people with inflammatory bowel disease (IBD) who are in remission. Fifteen adults with Crohn's disease or ulcerative colitis will use a small device for 28 days and undergo brain scans before and after. The goal is to see if this approach is feasible and whether it affects brain networks linked to stress and emotion.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Gastroenterology Department / Independent Public Healthcare Centre of the Ministry of Interior and Administration in Gdansk

    Gdansk, Pomeranian Voivodeship, 80-104, Poland

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Non-invasive vagus nerve stimulation device (Nurosym)

What this could lead to

If it works, this could point toward a drug-free way to manage IBD by calming the brain-gut connection.

What could go wrong

This is a very early, small pilot study with only 15 people. It is designed to test feasibility, not effectiveness, so results may not lead to a treatment.

Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.