New rehab program aims to ease Veterans' brain injury symptoms
NCT ID NCT07463027
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a 3-week outpatient rehab program can reduce long-lasting symptoms of traumatic brain injury (TBI) and related conditions like PTSD and depression in 416 veterans and first responders. Participants will complete surveys, and some will also give blood samples or get brain scans. The goal is to see if the program improves symptoms and quality of life compared to usual care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 3-week interdisciplinary outpatient rehabilitation program (IORP)
- What this could lead to
- If successful, this program could offer a practical way to reduce long-lasting symptoms and improve quality of life for veterans and first responders with TBI and related conditions.
- What could go wrong
- This is a pragmatic trial without a placebo control, so results may be influenced by participant expectations. The program is intensive and may not be suitable for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 416 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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May 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meets general eligibility requirements for site specific 3-week IORP * Capable of providing informed consent for IORP and study participation * English speaking * 18 to 65 years old Exclusion Criteria: * History of TBI of any severity in the past 6 months * Active substance use disorder that precludes study participation * Neurologic, psychiatric, or other medical condition that would prohibit full study participation * Active-duty military service member * Any other circumstance that, in the opinion of the investigator, would undermine the integrity or success of the project
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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BRAVE Program
Milwaukee, Wisconsin, 53226, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Machine learning may forecast brain decline after head injury